Search Keyword : Diabetes Mellitus


Disease List

CUI Disease
C0011849 Diabetes Mellitus
C0085207 Diabetes, Gestational
C0011860 Diabetes Mellitus, Non-Insulin-Dependent
C0011854 Diabetes Mellitus, Insulin-Dependent
C0034818 Insulin Receptor
C0271695 Pineal hyperplasia AND diabetes mellitus syndrome
C0155733 Atherosclerosis of aorta
 others no cui disease

Disease Information

CUI  C0034818
Disease Name  Insulin Receptor
Synonymous  Insulin Receptors
Receptors, Insulin
Receptor, Insulin
Insulin-Dependent Tyrosine Protein Kinase
Insulin Receptor Protein-Tyrosine Kinase
Insulin Receptor Protein Tyrosine Kinase
Insulin receptor site
Insulin receptor (substance)
INSR
Description  A cell surface receptor for INSULIN. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precusor protein. The receptor contains an intrinsic tyrosine kinase domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the LIVER; MUSCLE; and ADIPOSE TISSUE.

a tyrosine kinase type, transmembrane receptor, which places it in the growth factor receptor family, even though insulin is usually considered a hormone. 


Gene Information

CUI Disease Gene Symbol Table Name
 C0034818 INSULIN RECEPTOR; INSR INSULIN RECEPTOR, DEFECT IN, WITH INSULIN-RESISTANT DIABETES MELLITUS AND ACANTHOSIS NIGRICANS, INCLUDE INSR  OMIM2Gene 

SNP Information

CUI OMIM ID OMIM Variant ID Disease Gene Symbol Changes SNP ID Table Name
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